z atad fmk Search Results


94
R&D Systems z atad fmk
Z Atad Fmk, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Becton Dickinson z-atad-fmk
Z Atad Fmk, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MBL International z-ala-thr-ala-asp(ome)-fmk (z-atad-fmk)
Z Ala Thr Ala Asp(ome) Fmk (Z Atad Fmk), supplied by MBL International, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/z-ala-thr-ala-asp(ome)-fmk (z-atad-fmk)/product/MBL International
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MBL Life science z-atad-fmk
Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor <t>Z-VAD-fmk</t> (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor <t>Z-ATAD-fmk</t> (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001
Z Atad Fmk, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/z-atad-fmk/product/MBL Life science
Average 90 stars, based on 1 article reviews
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MBL International z-alathr-ala-asp(ome)-fmk(z-atad-fmk
Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor <t>Z-VAD-fmk</t> (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor <t>Z-ATAD-fmk</t> (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001
Z Alathr Ala Asp(ome) Fmk(z Atad Fmk, supplied by MBL International, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/z-alathr-ala-asp(ome)-fmk(z-atad-fmk/product/MBL International
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MBL Life science caspase-12 inhibitor z-atad-fmk
Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor <t>Z-VAD-fmk</t> (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor <t>Z-ATAD-fmk</t> (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001
Caspase 12 Inhibitor Z Atad Fmk, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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92
R&D Systems caspase 12
Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor <t>Z-VAD-fmk</t> (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor <t>Z-ATAD-fmk</t> (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001
Caspase 12, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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N/A
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
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Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor Z-VAD-fmk (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor Z-ATAD-fmk (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001

Journal: Cell Death & Disease

Article Title: NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation

doi: 10.1038/cddis.2013.169

Figure Lengend Snippet: Cell death induced by CAPS-associated NLRP3 mutants was programmed cell death. ( a and b ) WT and mutant NLRP3-Tet-On-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to cathepsin B inhibitor CA074-Me (20 μ M), pan-caspase inhibitor Z-VAD-fmk (10 μ M), caspase-1 inhibitor Z-YVAD-cho (10 μ M), caspase-2 inhibitor, Z-VDVAD-fmk (10 μ M), caspase-3/7 inhibitor Z-DEVD-fmk (10 μ M), caspase-4 inhibitor Z-LEVD-fmk (10 μ M), caspase-8 inhibitor Z-IETD-fmk (10 μ M), caspase-9/11 inhibitor Z-LEHD-fmk (10 μ M) or caspase-12 inhibitor Z-ATAD-fmk (10 μ M). Cells were stained with 100 nM TOTO-3 for 5 min and analyzed by flow cytometry. ( c ) WT and mutant NLRP3-Tet-on-MC/9 cells were treated with 1 μ g/ml doxycycline for 12 h in addition to pan-caspase inhibitor Z-VAD-fmk or Boc-D-fmk (10/20/40 μ M). **, P <0.01; and ****, P <0.0001

Article Snippet: The pan-caspase inhibitors Z-VAD-fmk (R&D Systems), ac-VAD-cho (MERCK, Whitehouse Station, NJ, USA), Q-VD-OPh and Boc-D-fmk (BioVision, Milpitas, CA, USA), and specific caspase inhibitors Z-YVAD-fmk (MERCK), Z-VDVAD-fmk, Z-LEVD-fmk and Z-ATAD-fmk (MBL, Nagoya, Japan), Z-YVAD-cho, Z-DEVD-fmk, Z-IETD-fmk and Z-LEHD-fmk (R&D Systems), Z-FA-fmk (BD Pharmingen) were purchased.

Techniques: Mutagenesis, Staining, Flow Cytometry